Comprehensive meta analysis serial
The study findings indicate that one SARS-CoV-2-infected person is likely to infect 3 persons, supporting that COVID-19 is a highly contagious disease. As time has progressed, predicted R0 and Rt values had decreased globally. Subgroup analysis by geographical region and date of publication revealed variations over both time and geography in calculated R0 and Rt values.
Our results demonstrated the mean SI was 5.45 days, with the 95% confidence interval (CI) of 4.23 to 6.66. Heterogeneity and publication bias were assessed.Ī total of 39 articles met the eligibility criteria. A continuous random-effect model was applied using the DerSimonian-Laird (inverse variance) method. Web of Science, PubMed, Scopus, and Science Direct searching up to May 10, 2020, was performed. One of the parameters which influence the calculations is the SI, the period between symptom onset in an infector and an infectee.
To assess the rate at which an infectious disease can spread in a population, the 2 measures, R0 and Re or Rt, are widely used.
COMPREHENSIVE META ANALYSIS SERIAL SERIAL
The aim of this study was to systematically review and meta-analyze all literature reporting the basic reproductive number (R0), effective reproductive number (Re or Rt), and the serial interval (SI) values of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection.